CHM-360 CH 4-5

What is the primary driving force for protein folding?

• a) Electrostatic interactions between charged amino acid side chains
  

• b) Hydrophobic interactions between nonpolar amino acids

• c) The formation of hydrogen bonds between peptide bonds

• d) The formation of covalent disulfide bonds between cysteine residues

Which of the following is true about peptide bond formation?

• a) Peptide bonds are formed through a condensation reaction between two amino acids.
  

• b) Peptide bonds are broken through hydrolysis during protein synthesis.

• c) Peptide bonds are covalent bonds formed by the interaction of two non-polar side chains.

• d) Peptide bonds result in the formation of a disulfide bridge.

The diagram shows a bond forming between two amino acids. What is the name of this reaction?

• Dehydration Synthesis
• Hydrolysis
• Pepysis
• Oxidation

The structural diagram demonstrates two joined amino acids. Which arrow points to the peptide bond?

• 1

• 2

• 3

• 4

Which of the following interactions is least likely to contribute to the tertiary structure of a protein?

• b) Ionic bonds between charged side chains

• a) Hydrogen bonds between backbone atoms

• d) Covalent bonds between peptide bonds

• c) Van der Waals interactions between nonpolar side chains

Which amino acid is most likely involved in the formation of disulfide bonds?

• a) Serine

• b) Tyrosine

• c) Cysteine

• d) Glutamine

How does the structure of amino acids determine the structure and function of proteins?

• A) The number of amino acids in a protein determines its function

• B) The sequence of amino acids determines the protein's structure, which in turn determines its function

• C) Only the amino acids with hydrophobic side chains determine a protein's structure and function

• D) The structure of amino acids is not related to the structure and function of proteins

What is the effect of denaturation on a protein's structure?

• A) It rearranges the primary structure

• B) It only affects the quaternary structure

• C) It unfolds the protein, disrupting the secondary, tertiary, and quaternary structures

• D) It strengthens the protein's structure

The order of amino acids determines the ______ and ultimately the function of a protein.

• shape

• color

• flavor

• texture

At what pH does histidine exist in both protonated and deprotonated forms, giving it a dual role in protein function?

• a) pH 4.0

• b) pH 6.0

• c) pH 7.4

• d) pH 10.0