Cytoskeletal Dynamics Quiz

What are the two main cytoskeletal components discussed in the paper?

• Microfilaments and intermediate filaments

• Microfilaments and microtubules

• Microtubules and septins

• Intermediate filaments and septins

What mechanism is described for the movement of the endoplasmic reticulum (ER) along microtubules?

• Retrograde transport

• Sliding and TAC-mediated movement

• Diffusion

• Passive transport

What is one proposed model for how STIM1 influences ER motility in relation to calcium dynamics?

• By promoting ER fragmentation during high calcium levels

• By facilitating the recruitment of dynein to the ER

• By controlling the polymerization of actin filaments

• By aggregating at ER-plasma membrane junctions to enhance SOCE

Which microtubule motor proteins are mentioned as responsible for transporting vesicles away from the Golgi to the periphery?

• Dyneins

• Kinesins

• Myosins

• All of the above

Which of the following accurately describes the role of Arp2/3 complex in actin dynamics as discussed in the paper?

• It serves solely as a nucleator for linear actin filaments.

• It generates branched actin networks essential for membrane protrusion.

• It stabilizes existing actin filaments during cell division.

• It is responsible for the depolymerization of actin filaments.

Which specific feature of neurons presents unique challenges for organelle distribution and dynamics?

• Large cell body size

• High cytoskeletal density

• Polarized structure

• Inability to form synapses

What is the primary mechanism through which actin filaments affect membrane dynamics during yeast endocytosis?

• Hydrolysis of ATP

• Polymerization of actin filaments

• Binding of dynein motor proteins

• Stabilization by spectrin

Which actin-binding protein is responsible for capping the plus end of actin filaments to regulate their growth?

• Cofilin

• CapZ

• Tropomyosin

• Gelsolin

In the context of cellular motility, how do actin filaments contribute to lamellipodia formation?

• By stabilizing the cell membrane

• By providing a rigid structure

• By forming branched networks that push the membrane forward

• By inhibiting myosin activity

What is the role of myosin motors in relation to actin filaments?

• They sever actin filaments.

• They transport cargo along actin filaments.

• They stabilize F-actin structures.

• They inhibit actin polymerization.