Selectivity and Stereochemistry

What does a dashed line indicate in a molecular structure?

• The bond is extending behind the plane of the drawing surface

• The bond is protruding out from the plane of the drawing surface

• The stereochemistry of the bond is unknown

• The bond exists in the plane of the drawing surface

Which term describes the preferential reactivity of one site over another in the same functional group?

• Chemoselectivity

• Regioselectivity

• Stereoselectivity

• Selectivity

According to Markovnikov's Rule, where does hydrogen add in the addition of H2O to an alkene?

• To the less substituted carbon

• To the more substituted carbon

• To the side with the most hydrogens

• To the side with the least hydrogens

What is the outcome of the Friedel-Crafts reaction?

• Substitution of H to the alkyl or acyl group on a benzene ring

• Addition of H2O to an alkene

• Formation of cyclic molecules from conjugate dienes

• Reduction of C=C over C=O

What does chemoselectivity refer to?

• The selectivity of one regioisomer over another

• The selectivity of one reaction pathway over another

• The selectivity of one functional group over another

• The selectivity of one stereoisomer over another

Which reaction is an example of anti-Markovnikov's addition?

• Addition of H2O (acid catalyzed hydration)

• Addition of HBr with H2O2

• Addition of H2O (oxymercuration-demercuration)

• Addition of H2O with H2SO4

What type of isomers are diastereomers?

• Compounds with a plane of symmetry

• Nonsuperposable mirror images

• Compounds with identical physical properties

• Stereoisomers that are not mirror images

What is the role of vanadyl acetylacetonate in epoxidation?

• To reduce carbonyl compounds

• To control chemoselectivity

• To facilitate hydrogenation

• To promote regioselectivity

Which of the following reactions is NOT an example of regioselectivity?

• Addition of HBr with H2O2

• Diels-Alder reactions

• Addition of H2O (acid catalyzed hydration)

• Reduction of C=C over C=O

What is a meso compound?

• A compound with no chiral centers

• A compound with only one chiral center

• A compound that is superposable on its mirror image

• A compound that has a plane of symmetry