Blood Component Preparation Quiz

A 67-year-old patient with chronic lymphocytic leukemia develops symptomatic anemia. The physician requests a blood component that will minimize the risk of alloimmunization and febrile non-hemolytic transfusion reactions. Which component is most appropriate?

• Whole blood

• Irradiated RBCs

• Leukocyte-reduced RBCs

• Washed RBCs

What is the most common method for preparing platelet concentrates from whole blood?

• Apheresis

• Centrifugation (soft spin followed by hard spin)

• Sedimentation

• Filtration

A plateletpheresis unit from a single donor is equivalent to how many units of random donor platelets?

• 2–3

• 4–5

• 6–8

• 8–10

Which of the following components must be irradiated before transfusion to an immunocompromised patient to prevent TA-GVHD?

• Fresh frozen plasma

• Cryoprecipitate

• RBCs

• Platelets

Cryoprecipitate is rich in which of the following coagulation factors?

• Factor II

• Factor V

• Factor VIII and fibrinogen

• Factor IX and X

A 10-year-old child undergoing chemotherapy is severely neutropenic and febrile. Which blood component is indicated?

• Platelet concentrate

• Leukocyte-reduced RBCs

• Granulocyte concentrate

• Fresh frozen plasma

Which component is appropriate for a patient with hemophilia A?

• Cryoprecipitate

• FFP

• Platelets

• Whole blood

After whole blood is collected and refrigerated without separation, for how long can platelets be effectively recovered?

• 4 hours

• 8 hours

• 12 hours

• 24 hours

A 29-year-old woman with von Willebrand disease is scheduled for surgery. Which product should be administered preoperatively?

• Fresh frozen plasma

• Cryoprecipitate

• Platelet concentrate

• Washed RBCs

What is the maximum storage duration of thawed FFP at 1–6°C?

• 6 hours

• 12 hours

• 24 hours

• 5 days