Drug Affinity and Intrinsic Activity

A drug that has affinity, but no intrinsic activity is an _________

• antagonist

• agonist

• enzyme

• substrate

A PARTIAL AGONIST HAS AFFINITY BUT LACKS FULL ___________.

• efficacy

• potency

• selectivity

• affinity

The blood-brain barriers exist because of the unique structure of CNS _________?

• capillaries (or endothelial cells)

• neurons

• astrocytes

• microglia

Drugs that act in the CNS can exert their effects at several sites that alter _________

• synaptic transmission

• blood pressure

• heart rate

• muscle contraction

28. BENZODIAZEPINES AUGMENT THE INHIBITORY EFFECTS OF _______.

• GABA

• Dopamine

• Serotonin

• Acetylcholine

Non-benzodiazepine sedatives such as eszopiclone have less residual drowsiness due to their short _________?

• half-life

• duration

• onset

• bioavailability

Norepinephrine and serotonin reuptake inhibition occurs with SNRIs and _______.

• TCAs (Tricyclic Antidepressants)

• SSRIs (Selective Serotonin Reuptake Inhibitors)

• MAOIs (Monoamine Oxidase Inhibitors)

• Benzodiazepines

Non-benzodiazepine sedatives such as eszopiclone have less residual drowsiness due to their short _________?

• half-life

• duration

• onset

• bioavailability

CNS stimulants that are direct sympathomimetics bind to _____ receptors in the CNS.

• adrenergic

• cholinergic

• dopaminergic

• histaminergic

A patient taking a non-selective beta-blocker, such as propranolol, may experience which of the following during exercise?

• Increased exercise tolerance

• Bronchoconstriction

• Hypoglycemia

• Hyperthermia