Psychopharmacology MCQs

Which of the following is a selective serotonin reuptake inhibitor (SSRI)?

• Imipramine

• Fluoxetine

• Bupropion

• Trazodone

Which antidepressant carries the highest risk of seizure at high doses?

• Venlafaxine

• Paroxetine

• Bupropion

• Fluoxetine

Which class of drugs requires a strict tyramine-free diet?

• SSRIs

• MAOIs

• SNRIs

• TCAs

What is the mechanism of action of benzodiazepines?

• Dopamine receptor blockade

• GABA-A receptor modulation

• NMDA receptor antagonism

• Acetylcholine inhibition

Which antipsychotic is most associated with agranulocytosis?

• Risperidone

• Olanzapine

• Clozapine

• Haloperidol

Which neurotransmitter is primarily increased by stimulants like methylphenidate?

• Serotonin

• GABA

• Norepinephrine

• Acetylcholine

Which mood stabilizer is known to cause nephrogenic diabetes insipidus?

• Lamotrigine

• Lithium

• Valproate

• Carbamazepine

What is the therapeutic plasma level range for lithium in acute treatment?

• 0.2-0.5 mEq/L

• 0.6-1.5 mEq/L

• 2.0-2.5 mEq/L

• 5.0-6.5 mEq/L

Which brain region shows hyperactivity in OCD patients?

• Hippocampus

• Orbitofrontal cortex

• Dorsolateral PFC

• Brainstem

Which SSRI has the longest half-life?

• Fluvoxamine

• Paroxetine

• Citalopram

• Fluoxetine