Pharm Ch 31-32-33

Drugs that antagonize the action of histamine, commonly the H1 receptor antagonists

• antihistamines

• analgesics

• antipyretics

• antibiotics

Used to relive nasal obstruction and discharge

• Nasal decongestants

• Antihistamines

• Corticosteroids

• Expectorants

A viral infection of the upper respiratory tract, is the most common respiratory tract infection

• Common Cold

• Flu

• Pneumonia

• Bronchitis

Type II reaction

• Responses mediated by IgE, causing allergic reactions and asthma

• Responses mediated by IgG or IgM, generating direct damage to the cell surface

• Responses mediated by IgA, primarily involved in mucosal immunity

• Responses mediated by IgD, playing a role in B cell activation

Administering anticholinergic drugs via the _____ route instead of the _____ route results in less thickening of respiratory secretions and therefore a reduced incidence of mucus-plugged airways.

• systemic, respiratory

• oral, intravenous

• respiratory, systemic

• topical, subcutaneous

Can be a result of using nasal spray/solution for more than 3 days

• rebound nasal congestion

• chronic sinusitis

• allergic rhinitis

• nasal polyps

The most common adverse effect of albuterol

• muscle tremors

• dry mouth

• nausea

• headache

Adverse effects for dextromethorphan

• Nausea, drowsiness, rash and difficulty breathing

• Increased energy and alertness

• Severe headaches and migraines

• Weight gain and insomnia

Prototype for Immunosuppresant Monoclonal Antibodies

• omalizumab (Xolair)

• rituximab (Rituxan)

• infliximab (Remicade)

• adalimumab (Humira)

Common adverse effects of inhaled beclomethasone

• headache

• nausea

• dry mouth

• dizziness