Antimalarial Drugs Quiz

What is the mechanism of action of chloroquine?

• Inhibits DNA synthesis

• Interferes with heme detoxification

• Blocks folic acid synthesis

• Inhibits protein synthesis

Which drug is classified as a tissue schizonticide?

• Chloroquine

• Mefloquine

• Quinine

• Primaquine

What is the primary aim of malaria treatment?

• Reducing fever

• Complete eradication of all parasites

• Symptomatic relief only

• Preventing transmission to mosquitoes

What is the first-line treatment for uncomplicated P. falciparum malaria?

• Oral quinine + doxycycline

• Oral primaquine

• Oral artemether + lumefantrine

• Oral chloroquine

What is the role of gametocides in malaria treatment?

• Relieve symptoms

• Eliminate liver hypnozoites

• Prevent transmission to mosquitoes

• Kill blood-stage parasites

Which antimalarial drug is known for its rapid action?

• Mefloquine

• Doxycycline

• Artemisinin

• Lumefantrine

What is the primary concern regarding the use of antimalarial drugs?

• Side effects

• Availability of vaccines

• Emergence of drug resistance

• Cost of treatment

What is the mechanism of action of artemisinin?

• Blocks protein synthesis

• Releases free radicals from the endoperoxide bridges

• Release free radicals from redox cycling

• Inhibits heme detoxification

Which of the following is a slow-acting blood schizonticide?

• Artemisinin

• Chloroquine

• Quinine

• Mefloquine

What is the recommended 1st line treatment for severe P. falciparum malaria?

• Oral primaquine

• IM quinine + doxycycline

• IV artesunate + lumefantrine

• Oral artemether + lumefantrine