Abrams Chapter 10

What is the primary goal of drug therapy for dyslipidemia?

• Increase HDL levels

• Decrease LDL cholesterol

• Reduce blood pressure

• Increase triglycerides

Which class of drugs is most effective in lowering LDL cholesterol?

• Bile acid sequestrants

• Fibrates

• Statins

• Niacin

What is a common adverse effect of statins?

• Constipation

• Myopathy

• Insomnia

• Rash

Which laboratory test should be monitored regularly in patients taking statins?

• Hemoglobin A1c

• Liver function tests

• Serum calcium

• White blood cell count

Which medication inhibits the absorption of cholesterol in the small intestine?

• Ezetimibe

• Atorvastatin

• Gemfibrozil

• Niacin

Which of the following is true about bile acid sequestrants?

• They are the first-line treatment for hyperlipidemia

• They are well absorbed in the gastrointestinal tract

• They can interfere with absorption of fat-soluble vitamins

• They are primarily used to increase triglycerides

Niacin is known to:

• Lower LDL and raise HDL

• Raise LDL and lower HDL

• Increase triglycerides

• Cause constipation

What is the main adverse effect associated with niacin?

• Drowsiness

• Flushing

• Hypertension

• Muscle cramps

Fibrates are primarily used to:

• Decrease LDL

• Increase HDL

• Lower triglycerides

• Decrease blood pressure

Which of the following is a contraindication for statin use?

• Hypertension

• Type 2 diabetes

• Active liver disease

• Chronic kidney disease