Brain Metabolism Quiz

Which fuel source is primarily used by the brain under normal conditions?

• Fatty acids

• Ketone bodies

• Glucose

• Amino acids

Which of the following cannot cross the blood-brain barrier efficiently?

• Glucose

• Palmitate

• Linoleic acid

• Oxygen

Which process provides the most ATP per glucose molecule in the brain?

• Anaerobic glycolysis

• Fermentation

• Complete oxidation to CO₂

• Gluconeogenesis

What occurs when blood glucose falls below 1 mM in hypoglycemia?

• Increased neurotransmitter synthesis

• Enhanced memory function

• ATP depletion and neuronal death

• Elevated pH

Which metabolic condition can result from chronic alcoholism and lead to brain damage?

• Hyperglycemia

• Hypoglycemia

• Hypernatremia

• Acidosis

Which neurotransmitter synthesis is diminished due to pyruvate dehydrogenase inhibition?

• Serotonin

• Acetylcholine

• Dopamine

• GABA

Which molecule leads to excitotoxicity in hypoglycemic encephalopathy?

• Acetylcholine

• GABA

• Glutamate

• Dopamine

Which vitamin is required by methylmalonyl-CoA mutase?

• Folate

• Vitamin D

• Vitamin B12

• Niacin

In prolonged fasting, what becomes the primary fuel for the brain?

• Amino acids

• Glucose

• Fatty acids

• Ketone bodies

Which condition is characterized by EEG becoming isoelectric?

• Hyperglycemia

• Mild hypoxia

• Severe hypoglycemia

• Ketosis