Which of the following is an internal defense mechanism?

Keratin coating epithelial cells

Surfactant in mucosal secretions

Normal flora is best described by which of the following statements?

A mix of bacteria that are normally present and do not typically cause disease

One type of bacteria that is normally present and never causes disease

A mix of bacteria that are normally present that never cause disease

One type of bacteria that is normally present and that we constantly are defending against

Acute phase reactants act by doing which of the following?

Promoting adherence to pathogens

Promoting destruction by releasing proteolytic enzymes

Limiting adherence to pathogens

Which of the following occurs during an inflammatory response?

Decreased permeability of fluid through the vessels

Constriction of the blood vessels

Migration of macrophages within 30 mins.

Which inflammatory response is responsible for the symptom of swelling?

Increased permeability of fluid through vessels

The term “human leukocyte antigen” is synonymous with:

major histocompatibility complex.

Characteristics of heterophile antigens include which of the following?

Found in unrelated plants or animals but cross-react with the same antibody

The purpose of negative selection of B cells is to:

eliminate B cells that are specific for self-antigens.

eliminate B cells that don't express mu.

prevent activation of B cells in the bone marrow.

direct more B cells to become plasma cells.

A plasma cell differs from a B cell in which way?

Only plasma cells secrete circulating antibody.

Plasma cells are only found in peripheral blood.

Plasma cells secrete cytokines.

Plasma cells are an immature form in B-cell development.

The function of CD4+ T cells is:

to kill virally infected cells.

Which of the following is characteristic of IgG?

Provides immunity for the newborn

First class of antibody to appear

The least abundant antibody in serum

Identify the correct pairing of an immunoglobulin and its property.

IgM: immunoglobulin produced by a T cell

IgE: major immunoglobulin of secondary response

Which of the following is a characteristic of IgA?

It is the primary response antibody.

Which is a characteristic of IgM?

It increases greatly in the secondary response.

Identify the true statement about the anamnestic response versus the primary antibody response.

The primary response involves predominantly an increase in IgG antibodies, whereas the anamnestic response involves predominantly an increase in IgM antibodies.

The primary response has a long lag phase; the anamnestic response has a short lag phase.

The primary response has a short lag phase; the anamnestic response has a long lag phase.

The primary response involves a rapid increase in antibody titer, whereas the anamnestic response involves a rapid decrease in antibody titer.

Which option best describes a monoclonal antibody?

All antibodies of any one particular class

Antibody made against multiple epitopes

Antibody made by a variety of B cells

Antibody made from a single antibody-producing cell

An Fab fragment consists of:

one light chain and one-half of a heavy chain.

one light chain and an entire heavy chain.

Characteristics of cytokines include which of the following?

They are chemical messengers that regulate the immune system.

They are directly cytotoxic to bacteria.

They are produced primarily by the liver.

A cytokine “storm” is a:

massive, pathological overproduction of cytokines that contributes to pathogenesis.

systemic transfer of reactive macrophages induced by cytokines.

cytokine-mediated invasion of an infected wound by leukocytes.

psychological response to cytokines that bind hypothalamic receptors.

Identify the main action of IL-6.

Stimulates synthesis of acute-phase proteins.

Stimulates red blood cell production.

Inhibits antigen presentation by macrophages.

Decreases activation of T and B cells.

Basic Immunology Final Review

Authored by Jesse Manske

Science

University

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MULTIPLE CHOICE QUESTION

20 sec • 1 pt

Phagocytosis is appropriately categorized into which of the following?

Adaptive immunity

Innate immunity

Humoral immunity

Specific immunity

MULTIPLE CHOICE QUESTION

20 sec • 1 pt

A patient with a viral infection that has initiated their cell-mediated immunity might have an increased number of which leukocytes in their peripheral blood?

Lymphocytes

Neutrophils

Monocytes

Basophils

MULTIPLE CHOICE QUESTION

20 sec • 1 pt

Which of the following cells can phagocytize foreign microbes?

T lymphocytes

B lymphocytes

Macrophages

Natural killer (NK) cells

MULTIPLE CHOICE QUESTION

20 sec • 1 pt

Which of the following cells is a phagocytic cell that has a similar morphology to nerve cells?

Neutrophils

Dendritic cells

Mast cells

Macrophages

MULTIPLE CHOICE QUESTION

20 sec • 1 pt

Secondary lymphoid tissues that are located near our joints and serve as a collecting duct for lymph fluid are:

spleen cells.

lymph nodes.

MALT.

CALT.

MULTIPLE CHOICE QUESTION

20 sec • 1 pt

Foreign microbes that enter through a cut in our hand should expect defense from which lymphoid tissue?

CALT

Spleen

MALT

Thymus

MULTIPLE CHOICE QUESTION

20 sec • 1 pt

Which of the following is correct?

adhesion molecules.

antibodies.

chemotaxins.

clusters of differentiation.

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Basic Immunology Final Review

Phagocytosis is appropriately categorized into which of the following?

A patient with a viral infection that has initiated their cell-mediated immunity might have an increased number of which leukocytes in their peripheral blood?

Which of the following cells can phagocytize foreign microbes?

Which of the following cells is a phagocytic cell that has a similar morphology to nerve cells?

Secondary lymphoid tissues that are located near our joints and serve as a collecting duct for lymph fluid are:

Foreign microbes that enter through a cut in our hand should expect defense from which lymphoid tissue?

Which of the following is correct?

A patient with antibodies in their serum to a particular virus has activated which immune cells?

Which lymphocyte is part of our innate immunity?

Which of the following is an internal defense mechanism?

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