MUTATIONS IN CANCER

How much types of mutations are?

• 2

• 8

• 4

• 5

Which genes are affected by cancer?

• DNA repair genes

• Tumor suppressor genes

• Oncogenes

• All of the above

Which are some causes of cancer?

• UV radiations, chronic inflammation, stress, tobacco

• Stress, depression, sadness, mental ilnesses

• Eat too much fat

• Tobacco, alcohol, bad alimentation

The loss of cell cycle control is a consequence of mutations

• True

• False

What is the normal function of the BRCA 1 & 2?

• Increase the speed of cell division

• Help to supress tumors by repairing damaged DNA

• Store genetic information for reproduction

• Generate proteins for energy production in cells

What happens if there is a mutation in BRCA 1 & 2?

• It improves DNA repair speed, making cells more resistant to damage

• It causes faster wound healing

• It strengthens muscle fibers and improves physical endurance

• Increase the risk of developing breast and ovarian cancer

What genetic change occurs in chronic myeloid?

• Mutation in TP53

• Deletion of chromosome 21

• BCR-ABL translocation

• Duplication of MYC gene

Which two genes fuse together as a result of the translocation described in the slide?

• BCR and ABL1

• BRCA1 and BRCA 2

• MYC and RAS

• TP53 and KRAS

All mutations cause cancer

• True

• False