Hematology Bootcamp Assessment

The major iron storage compound in the body is:

• Ferritin

• Hemoglobin

• Hemosiderin

• Transferrin

A 32-year-old female presents with fatigue. CBC shows: Hb 9.5 g/dL, Hct 30%, MCV 72 fL. Serum ferritin: 8 ng/mL, Serum iron: 20 µg/dL, TIBC: 450 µg/dL, % saturation: 4%. The most likely diagnosis is:

• Anemia of chronic disease

• Iron deficiency anemia

• Thalassemia minor

• Aplastic anemia

A 48-year-old male with rheumatoid arthritis has: Hb 10.8 g/dL, Hct 33%, MCV 82 fL. Serum ferritin: 300 ng/mL, Serum iron: 40 µg/dL, TIBC: 220 µg/dL, % saturation: 18%. The most likely diagnosis is:

• Iron deficiency anemia

• Anemia of chronic disease

• Thalassemia minor

• Sideroblastic anemia

Which of the following anemias results from decreased synthesis of globin chains?

• Sideroblastic anemia

• Iron deficiency anemia

• Thalassemia

• Megaloblastic anemia

Megaloblastic anemia is most commonly caused by deficiency of:

• Iron

• Vitamin B12 or folate

• Vitamin C

• Vitamin K

Pernicious anemia is caused by:

• Lack of intrinsic factor

• Iron loss

• Chronic blood loss

• RBC membrane defect

Sickle cell disease is caused by a mutation in the gene coding for:

• Alpha-globin

• Beta-globin

• Gamma-globin

• Delta-globin

Plasma cells develop from which cell line?

• Myeloid

• Lymphoid (B-cell)

• Monocytic

• Erythroid

A key peripheral smear finding in G6PD deficiency is:

• Howell-Jolly bodies

• Heinz bodies

• Basophilic stippling

• Target cells

Aplastic anemia is typically associated with which bone marrow finding?

• Hypercellular marrow

• Hypocellular marrow

• Sideroblasts

• Increased blasts