Pharmacology Quiz 4

Which type of hypersensitivity reaction is Stevens–Johnson syndrome most commonly associated with?

• Type I

• Type II

• Type III

• Type IV

Which drug is most likely to cause “gray baby syndrome” due to immature glucuronidation?

• Gentamicin

• Chloramphenicol

• Erythromycin

• Vancomycin

Which combination can precipitate serotonin syndrome?

• SSRI + MAOI

• NSAID + ACE inhibitor

• Warfarin + Vitamin K

• Beta-blocker + Digoxin

Which antibiotic can dangerously prolong the QT interval, especially with other QT-prolonging agents?

• Amoxicillin

• Azithromycin

• Tetracycline

• Penicillin G

Which drug interaction leads to “cheese reaction” (hypertensive crisis)?

• MAOI + Tyramine-rich food

• SSRI + Grapefruit juice

• Aspirin + Alcohol

• Metformin + Cimetidine

Which TDM parameter is most crucial for aminoglycosides?

• Peak level

• Trough level

• AUC

• Steady state

Which anticonvulsant requires monitoring of trough levels to avoid toxicity?

• Phenytoin

• Lamotrigine

• Levetiracetam

• Gabapentin

Which drug combination can lead to “Red Man Syndrome”?

• Vancomycin rapid infusion

• Rifampin + INH

• Gentamicin + Furosemide

• Aspirin + Methotrexate

Which adverse effect is associated with long-term use of high-dose corticosteroids?

• Agranulocytosis

• Osteoporosis

• Stevens–Johnson syndrome

• Ototoxicity

Which drug causes dose-dependent gingival hyperplasia?

• Phenytoin

• Methotrexate

• Carbamazepine

• Amiodarone