Chapter 24 Pharm Final Review

What is candidiasis?

• A fungal infection caused by Candida fungi

• A bacterial infection of the skin

• A viral infection affecting the lungs

• A parasitic infection of the intestines

Which of the following best describes dermatophytes?

• Fungal parasites that grow in or on the skin

• Bacteria that infect the bloodstream

• Viruses that cause respiratory infections

• Parasites that live in the digestive tract

What are molds?

• Multicellular fungi that form fuzzy colonies

• Unicellular fungi of the genus Saccharomyces

• Single-celled organisms that cause disease

• Bacteria that thrive in moist environments

What is the role of glucan in fungal cells?

• It is part of the thick cell wall

• It is a component of the cell membrane

• It is a type of protein found in the cytoplasm

• It is a sugar used for energy storage

Which type of fungal infection is common in immunocompromised patients?

• Opportunistic infections

• Superficial infections

• Systemic infections

• Endemic infections

What is a challenge in drug therapy for fungal infections?

• Fungal cells are similar to human cells, leading to high toxicity risk.

• Fungal cells are resistant to all drugs.

• Fungal infections are always mild and do not require treatment.

• Fungal cells are identical to bacterial cells.

Which drug class binds ergosterol, causing membrane leakage or lysis?

• Polyenes

• Azoles

• Echinocandins

• Miscellaneous

What is the route of administration for Amphotericin B deoxycholate in systemic infections?

• Intravenous

• Oral

• Topical

• Inhalation

What is the initial serum half-life of Amphotericin B deoxycholate?

• Approximately 24 hours

• Approximately 48 hours

• Approximately 72 hours

• Approximately 12 hours

Which drug class blocks ergosterol synthesis, leading to defective membrane and cell death?

• Azoles

• Polyenes

• Echinocandins

• Miscellaneous