Bioinformatics

Who is regarded as the founder of bioinformatics?

• Margaret Dayhoff

• Rosalind Franklin
• Francis Crick
• James Watson

The Human Genome Project was completed in:

• 2003

• 2001

• 2004

• 2002

Which of the following is NOT a goal of bioinformatics?

• Storing biological data
• Developing computational tools
• Analyzing genetic sequences
• To predict weather patterns using models

Which of the following is a primary biological database?

• SWISS-PROT

• FlyBase

• GenBank

• TRANSFAC

Data in primary databases:

• Are curated and frequently changed

• Are archival and never altered after submission

• Are always generated from computational analysis

• Contain only protein sequences

Which is the only centralized database for 3D macromolecular structures?

• EMBL

• PDB

• DDBJ

• SWISS-PROT

Which of the following is a secondary database?

• EMBL

• DDBJ

• GenBank

• SWISS-PROT

FlyBase is an example of which type of database?

• Primary

• Secondary

• Specialized

• Proprietary

The building blocks of proteins are:

• Amino acids
• Carbohydrates
• Fatty acids
• Nucleotides

A peptide bond forms between:

• Two R groups

• Carboxyl group of one amino acid and amino group of next

• Hydrogen atom and side chain

• the amino group of one amino acid and the carboxyl group of next amino acid