Patient Profiles Quiz

Which drug modulates PPARγ, an established target in insulin resistance and metabolic syndrome?

• Bisoprolol

• Telmisartan

• Both

• Neither

In patients with hypertension and diabetes, Telmisartan is beneficial because it:

• Reduces blood pressure only

• Improves insulin sensitivity and lipid profiles

• Has no effect on metabolic parameters

• Increases glucose levels

What is the primary benefit of Bisoprolol in patients with mild to moderate hypertension?

• Metabolic neutrality

• Lipid profile improvement

• Blood pressure reduction only

• Kidney protection

In patients with stage 3-5 CKD hypertension, Bisoprolol has been shown to:

• Significantly reduce blood pressure and heart rate with good tolerance

• Worsen renal function

• Increase microalbuminuria

• Not be safe for use

Telmisartan's role in hypertensive patients with compelling indications such as post-MI is:

• Not effective

• Demonstrated to reduce cardiovascular morbidity and mortality

• Only reduces blood pressure, not cardiovascular events

• Causes adverse renal effects

The ONTARGET trial showed Telmisartan effectively reduces:

• Blood glucose only

• CV morbidity and mortality

• Lipid levels exclusively

• Microalbuminuria only

For young hypertensive patients with high resting heart rate, Bisoprolol is considered because it:

• Has no effect on heart rate

• Is superior in reducing BP and HR among selective β-blockers

• Worsens left ventricular hypertrophy

• Causes sexual dysfunction

In hypertensive patients with metabolic syndrome, Telmisartan helps by:

• Modulating PPARγ and improving insulin resistance

• Increasing triglyceride levels

• Causing weight gain

• Increasing blood pressure

What is a common effect of Bisoprolol on lipid and glucose levels?

• Increases glucose and triglycerides

• Reduces glucose, cholesterol, and triglycerides

• Has no effect on metabolic parameters

• Worsens lipid profile

In hypertensive patients with CKD, Bisoprolol is considered:

• Unsafe for use

• Effective for preservation of renal performance and safe with long-term benefits

• Ineffective in reducing blood pressure

• Only useful for heart rate control without renal benefits