Adrenal Steroids

Which zone of the adrenal cortex is primarily responsible for mineralocorticoid production?

• Zona fasciculata

• Zona reticularis

• Zona glomerulosa

• Zona medulla

Which hormone stimulates the adrenal cortex to produce cortisol?

• CRH

• ACTH

• GH

• TSH

Cushing syndrome is best characterized by:

• Excess aldosterone

• Deficiency of cortisol

• Excess cortisol

• Deficiency of ACTH

Which hormone is secreted by the zona fasciculata?

• Aldosterone

• DHEA

• Cortisol

• Testosterone

The adrenal androgens DHEA and androstenedione are produced primarily in the

• Zona glomerulosa

• Zona fasciculata

• Zona reticularis

• Adrenal medulla

Which of the following is a major effect of glucocorticoids on carbohydrate metabolism?

• Decreased gluconeogenesis

• Increased glucose utilization

• Decreased protein catabolism

• Increased hepatic glucose production

Which hormone is secreted by the zona fasciculata?

• Aldosterone

• DHEA

• Cortisol

• Testosterone

The most common enzyme deficiency in congenital adrenal hyperplasia (CAH) is:

• 11β-hydroxylase

• 17α-hydroxylase

• 21α-hydroxylase

• 18-hydroxylase

Clinical features of Cushing’s syndrome include all except

• Moon face

• Fat deposition on back of neck

• Hypoglycemia

• Hypertension

The dexamethasone suppression test is used to:

• Diagnose Addison’s disease

• Differentiate Cushing’s from pseudo-Cushing’s

• Measure aldosterone secretion

• Detect 21-hydroxylase deficiency