MI 2.1.1 Chronicles of a Genetic Counselor

By looking at the chromosomes how can you tell that this person is biologically female?

• Because there are two X chromosomes

• Because there are more chromosomes than in a male

This is known as Edwards Syndrome, can you identify the chromosomal mutation?

• Chromosomes 1 and 2 are bent

• There is no Y chromosome

• This persons chromosomes are normal

• There are 3 of chromosomes 18

Which chromosomal abnormality is responsible for Down syndrome?

• There is an extra chromosome 21

• There are three of chromosome 18

• There is only one X chromosome

• There is no Y chromosome

What is a karyotype?

• A karyotype is a type of DNA sequencing technique.
• A karyotype is a visual representation of the chromosomes in an individual's cells.
• A karyotype is a genetic disorder caused by an extra chromosome.
• A karyotype is a type of microscope used to study chromosomes.

What can be detected by analyzing a person's karyotype?

• The number of mitochondria in a cell

• The function of specific genes

• The sequence of DNA bases

• The presence of chromosomal abnormalities

Which of the following karyotypes would indicate a male with Klinefelter syndrome?

• 47, XXY

• 45, X

• 47, XYY

• 46, XX

This person has Angel Mans syndrome. What is different about their chromosomes?

• Chromosome 1 is misshapen

• Chromosomes 21 is too small

• They are missing one of chromosome 15

• Chromosomes 7 and 8 look weird

By looking at the chromosomes is this individual biologically male or female? How do you know?

• Female, because they have two X chromosomes

• Male, because they have one X and one Y chromosome

What is the mutation in this persons chromosomes?

• There is only one X

• 7 is shaped like a hockey stick

• There's an extra 21

• 1 is too curved

These are the chromosomes of someone with Kleinfelters syndrome. What is different about their chromosomes?

• There is only one Y chromosome

• One of the 5th chromosomes is too curved

• There is an extra X chromosome

• There are too few chromosomes