Exam 3: Chemistry Practice

ONE BEST ANSWER: Which of the following statements about Anidulafungin is CORRECT?

• Anidulafungin is a Thymidylate Synthase Inhibitor

• Anidulafungin belongs to the class of Triazole derived antifungal agents

• Anidulafungin is a Cyclic Peptide Analog

• Anidulafungin inhibits Peptidoglycan biosytnthesis

• Anidulafungin inhibits Ergosterol Biosythesis

ONE BEST ANSWER: Clotrimazole

• Inhibits Squalene Epoxidase

• Triazole derived antifungal agent

• Pyrimidine derived antifungal agent

• Indole derived antifungal agent

• Inhibits Ergosterol biosynthesis

Tags

NGSS.HS-PS1-2

ONE BEST ANSWER: Griseofulvin is an antifungal antibiotic produced from:

• Streptomycin tenebrarius

• Streptomyces griseofulvin

• Amycolatopsis griseofulvin

• Penicillium griseofulvin

• Penicillium chrysogenum

SATA: Which of the following statements about Griseofulvin is/are correct?

• Griseofulvin shows increased water solubility by reducing particle size

• Griseofulvin is isolated from Penicillium griseofulvin

• Griseofulvin inhibits cell mitosis by interfering with tubulin

• Griseofulvin is a pro-drug

• Griseofulvin is a fungal cell wall synthesis inhibitor

Tags

NGSS.HS-LS1-4

ONE BEST ANSWER: Which of the following statements about Nystatin is CORRECT?

• Nystatin is a weak acid

• Nystatin is an amphoteric substance

• Nystatin is a strong base

• Nystatin is a weak base

• Nystatin is a strong acid

Which of the following statements about Nystatin is/are correct? SATA

• Nystatin contains 38 membered lactone ring

• Glucosamine is attached to the macrolactone ring

• Nystatin contains 7 conjugated trans double bonds

• Nystatin is an amphoteric substance

• Nystatin contains 4 conjugated trans double bonds

SELECT ALL THAT APPLY: Amphotericin B contains

• Mycosamine

• 36 membered lactam ring

• 38 membered lactone ring

• 36 membered lactone ring

• Galactosamine

SATA: Which of the following statements about Amphotericin B is/are correct?

• Amphotericin B is a weak acid

• Amphotericin B contains 7 conjugated double bonds

• Amphotericin B is sparingly soluble in water and it must be given IV

ONE BEST ANSWER: Which of the following statements about Ketoconazole is CORRECT?

• Basic pH is required for Ketoconazole absorption

• Ketoconazole belongs to the class of triazole derived antifungal agents

• Ketoconazole is a 14α-demethylase inhibitor

• Ketoconazole is a fungal cell wall synthesis inhibitor

• Neutral pH is required for Ketoconazole absorption

Which of the following statements about Ketoconazole is/are correct? SATA

• Acidic pH is required for Ketoconazole absorption

• Ketoconazole is a fungal squalene epoxidase Inhibitor

• Ketoconazole belongs to the class of triazole derived antifungal agents

• Ketoconazole is a fungal ergosterol biosynthesis inhibitor

• Ketoconazole is a fungal 14α-demethylase inhibitor