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Disease Storyline Test Review

Authored by Meghan Loftus

Biology

KG - University

NGSS covered

Used 6+ times

Disease Storyline Test Review
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About

This quiz comprehensively covers the human immune system, targeting high school biology students at the 9th-12th grade level. The questions assess understanding of both innate and adaptive immunity, requiring students to distinguish between the body's first-line defenses and more sophisticated cellular responses. Students must demonstrate knowledge of key immune system components including white blood cell types (phagocytes, lymphocytes, B cells, T cells), their specific functions, and how they interact to protect against pathogens. The quiz requires mastery of immune system vocabulary including antigens, antibodies, pathogens, and the major histocompatibility complex (MHC), while also testing conceptual understanding of processes like clonal selection, inflammatory response, and the difference between primary and secondary immune responses. Students need to understand the molecular basis of immunity, including how vaccines work and why memory cells provide long-lasting protection against specific diseases. Created by Nancy Day, a Biology teacher in the US who teaches grade K-University. This comprehensive assessment serves multiple instructional purposes in the high school biology classroom, functioning effectively as a unit review, homework assignment, or formative assessment tool to gauge student understanding before a summative exam. The quiz can be used as a warm-up activity to activate prior knowledge at the beginning of immune system lessons, or as structured practice to reinforce learning after direct instruction on immune system components and functions. Teachers can assign this quiz as independent homework to help students self-assess their mastery of immune system concepts, or use it during class as a review activity before moving to more complex topics like autoimmune disorders or immunotherapy. The assessment aligns with NGSS standards HS-LS1-3 (planning and carrying out investigations to provide evidence that feedback mechanisms maintain homeostasis) and supports Common Core literacy standards in science through its emphasis on precise scientific vocabulary and conceptual understanding.

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35 questions

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1.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

What is the job of the immune system?

To protect your body from drugs and medicine
To protect your body from air and water
To protect your body from pathogens
To protect your body from itself

2.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

Disease-causing microorganism, such as a bacterium or virus.

pathogen 
allergen
prion 
antigen 

3.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

  A substance or part of a substance (living or nonliving) that the immune system recognizes as foreign and activates the immune system and reacts with immune cells or their products, such as antibodies.

pathogen 
allergen 
antigen 
antibody

4.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

What initiates an immune response?

antibody
antigen
histamine
antibiotic

5.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

A protein molecule released by a B cell that binds to specific antigens.

antigen
antibody
allergy
prion

6.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

Antigens prepared in such a way that when injected or taken orally they induce active immunity without causing disease.

antigen
spleen
B cell
vaccine

7.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

How is the secondary immune response different than the primary immune response?

faster and more antibodies produced
faster and higher fever
more antibodies and more phloem 
more blood filtered through liver

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