Understanding OCD: Genetics and Neurotransmitters

This video is part two of a lesson on OCD, focusing on biological explanations. It covers the role of genes, neurotransmitters, and brain structures in OCD. The video discusses specific genes like COMT and SERT, neurotransmitters such as serotonin and dopamine, and brain regions like the orbital frontal cortex. It also evaluates these explanations and provides exam tips, emphasizing the diathesis-stress model as a comprehensive approach.

What are the three main biological explanations for OCD discussed in the video?

• Hormones, lifestyle, and environment

• Diet, exercise, and sleep

• Genes, neurotransmitters, and brain structures

• Medication, therapy, and support groups

Which gene is involved in the production of catechol-O-methyltransferase (COMT)?

• COMT gene

• SERT gene

• DRD4 gene

• HTR2A gene

What does the SERT gene affect in the brain?

• Dopamine production

• Serotonin transport

• Norepinephrine levels

• GABA receptors

According to the diathesis-stress model, what is the 'diathesis'?

• Lifestyle choice

• Psychological trauma

• Genetic vulnerability

• Environmental stressor

Which of the following is NOT considered an environmental stressor that could trigger OCD?

• Divorce

• Death of a loved one

• Balanced diet

• Stress at work

Which model suggests that both genetic vulnerability and environmental stressors are necessary for the development of OCD?

• Diathesis-stress model

• Monoamine hypothesis

• Cognitive-behavioral model

• Psychodynamic model

What neurotransmitter is associated with mood regulation and is implicated in OCD?

• GABA

• Norepinephrine

• Serotonin

• Dopamine

Which neurotransmitter is linked to compulsive behaviors in animal studies?

• Serotonin

• Dopamine

• Norepinephrine

• Acetylcholine

What brain structure is involved in relaying worrying information and triggering compulsive behaviors in OCD?

• Hippocampus

• Orbital frontal cortex

• Amygdala

• Thalamus

What happens in the orbital frontal cortex of OCD patients when their symptoms are active?

• Decreased activity

• Increased activity

• No change in activity

• Random activity