Serotonin Catabolism 1

Serotonin Catabolism 1

Assessment

Interactive Video

•

Science, Biology, Chemistry

•

University

•

Practice Problem

•

Hard

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Wayground Content

FREE Resource

The video explores serotonin's synthesis, roles, and catabolic pathways. It details the mechanisms of serotonin metabolism, including hydroxylation, sulfation, and glucuronidation, which increase molecule polarity for excretion. The video also covers serotonin oxidation to aldehyde and carboxylate, and non-enzymatic reactions, emphasizing the importance of these processes in terminating serotonin's biological activity.

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10 questions

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1.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the primary role of serotonin in the brain?

Enhancing mood and sleep

Increasing heart rate

Regulating blood pressure

Controlling appetite

2.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which enzyme family is primarily responsible for increasing the polarity of serotonin?

Protease

Lipase

Amylase

Cytochrome P-450

3.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the universal sulfate donor used in the sulfation of serotonin?

ATP

NADPH

PAPS

GTP

4.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which enzyme specifically catalyzes the sulfation of serotonin?

Sulfotransferase 1B1

Sulfotransferase 1A1

Sulfotransferase 1A3

Sulfotransferase 1A2

5.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the initial product formed when serotonin is oxidized by monoamine oxidase?

Serotonin glucuronide

Hydroxy indole acetaldehyde

Serotonin sulfate

5-hydroxy tryptophan

6.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which enzyme is responsible for the oxidation of serotonin into an aldehyde?

Glucuronyl transferase

Sulfotransferase

Cytochrome P-450

Monoamine oxidase A

7.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the fate of hydroxy indole acetaldehyde in serotonin catabolism?

It is excreted unchanged

It is reduced to serotonin

It is oxidized to 5-hydroxy indole acetate

It is converted to serotonin sulfate

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