Cytochrome P450 Electron Sources (P450 Reductase or Adrenodoxin)

The video explains how cytochrome P-450 receives electrons to activate molecular oxygen, focusing on two systems: the mitochondrial adrena doxin reductase system and the microsomal P-450 reductase system. It details the electron transfer process from NADPH to FAD and further to the heme iron, highlighting the differences between the two systems based on their cellular location. The video also discusses the applications of these systems in processes like steroid synthesis.

What is the primary source of electrons for the cytochrome P-450 electron transport chain?

• FMN

• NADPH

• FADH2

• ATP

In the mitochondrial system, which enzyme transfers electrons from FAD to adrena doxin?

• FMN reductase

• NADPH oxidase

• Adrena doxin reductase

• Cytochrome P-450 reductase

What is the role of adrena doxin in the mitochondrial electron transport chain?

• It oxidizes molecular oxygen.

• It transfers electrons to the heme iron of P-450.

• It synthesizes ATP.

• It acts as a coenzyme for NADPH.

Which flavin is involved in the electron transfer process in the smooth endoplasmic reticulum?

• FAD

• FMN

• Coenzyme Q

• NADH

In the smooth endoplasmic reticulum, what is the sequence of electron flow?

• NADPH -> FMN -> FAD -> Heme iron

• NADPH -> FAD -> Heme iron -> FMN

• NADPH -> FAD -> FMN -> Heme iron

• NADPH -> Heme iron -> FAD -> FMN

Which system is used by the cholesterol side chain cleavage enzyme?

• Peroxisomal system

• Cytosolic system

• Mitochondrial system

• Microsomal system

What is the main difference between the mitochondrial and microsomal P-450 systems?

• The source of electrons

• The location of the P-450 enzyme

• The type of heme iron used

• The auxiliary enzymes involved