Coenzyme A (CoA) Biosynthesis Pathway and Vitamin B5

The video tutorial explains the biosynthesis of coenzyme A, a crucial molecule in various biochemical processes. It covers the sources of vitamin B5, the structure of coenzyme A, and the detailed steps involved in its biosynthesis, including the role of enzymes and ATP. The tutorial concludes with a summary of the materials and steps required to synthesize coenzyme A.

Which of the following is NOT a dietary source of vitamin B5?

• Potato

• Broccoli

• Egg yolk

• Liver

What is the role of pantothenate kinase in the biosynthesis of coenzyme A?

• It hydrolyzes coenzyme A.

• It phosphorylates pantothenate.

• It adds a methyl group to pantothenate.

• It removes a phosphate group from ATP.

During the biosynthesis of coenzyme A, cysteine is added to which molecule?

• 4-phosphopantothenate

• Pantothenate

• Adenosine

• Coenzyme A

What is the function of phosphopantetheine decarboxylase in the biosynthesis pathway?

• It adds a phosphate group.

• It hydrolyzes ATP.

• It removes a CO2 group.

• It transfers an adenosine group.

Which enzyme is responsible for adding an adenosine group to 4-phosphopantetheine?

• Adenylyl transferase

• Cysteine synthetase

• Phosphopantetheine decarboxylase

• Pantothenate kinase

How many ATP molecules are used in the entire biosynthesis of coenzyme A?

• Two

• Five

• Three

• Four

Which of the following is NOT a precursor required for the biosynthesis of coenzyme A?

• Pantothenic acid

• ATP

• Glucose

• Cysteine