The Coronavirus Replication Cycle

What is the approximate size of the coronavirus RNA genome?

• 10,000 nucleotides

• 40,000 nucleotides

• 20,000 nucleotides

• 30,000 nucleotides

Which process is unique to coronavirus replication?

• Protein folding

• Ribosome frame shifting

• Cell division

• DNA replication

What role does the CEACAM-1 receptor play in coronavirus infection?

• It destroys the virus

• It binds to spike proteins to facilitate entry

• It replicates the virus

• It provides energy to the virus

What are polyproteins 1a and 1ab involved in?

• Protein synthesis

• Cell division

• Replication and transcription

• Energy production

What is the result of discontinuous transcription in coronavirus replication?

• Destruction of host cell

• Production of antibodies

• Creation of subgenomic mRNAs

• Formation of DNA strands

How do subgenomic mRNAs contribute to coronavirus replication?

• They destroy the host cell

• They convert RNA to DNA

• They are translated into viral proteins

• They are used to create antibodies

Where does the translation of subgenomic mRNAs occur?

• In the nucleus

• In the cytoplasm

• In the Rough ER

• In the mitochondria

What is the function of the RNA-dependent RNA polymerase in coronavirus replication?

• It transports RNA

• It breaks down proteins

• It transcribes RNA at different points

• It synthesizes DNA

What happens to the viral progeny after they are packaged in vesicles?

• They remain dormant

• They are released to infect other cells

• They convert into DNA

• They are destroyed by the host cell

What is the significance of the leader TRS in discontinuous transcription?

• It allows transcription to jump to a new start point

• It initiates DNA replication

• It binds to antibodies

• It marks the end of transcription