Cardiac Pharmacology [Part 2] Anti-thrombotics & Anti-coagulants

The video discusses various drugs used in cardiac pharmacology, focusing on anticoagulants and antiplatelets. It explains the physiology of blood vessels and the role of clotting factors, detailing how drugs like Warfarin, Heparin, and NOACs work to prevent clot formation. The video also covers the mechanisms of plasminogen activators and platelet inhibitors like aspirin and Plavix, highlighting their importance in managing blood clots.

What is the role of vitamin K in the coagulation cascade?

• It inhibits thrombin.

• It activates platelets.

• It matures clotting factors.

• It degrades fibrin.

Which enzyme is responsible for converting fibrinogen into fibrin?

• Plasmin

• Cyclooxygenase

• Thrombin

• Antithrombin III

How does warfarin function as an anticoagulant?

• By activating plasminogen

• By inhibiting vitamin K epoxide hydrolase

• By enhancing thrombin activity

• By blocking platelet receptors

What is the primary function of heparin in anticoagulation?

• It activates antithrombin III.

• It converts fibrinogen to fibrin.

• It inhibits vitamin K.

• It blocks platelet aggregation.

What is the main action of tissue plasminogen activators?

• They enhance platelet adhesion.

• They activate plasminogen to plasmin.

• They inhibit thrombin.

• They block vitamin K.

How does aspirin prevent blood clots?

• By inhibiting cyclooxygenase enzymes

• By activating plasmin

• By blocking vitamin K

• By enhancing thrombin activity

What is the function of the P2Y12 receptor on platelets?

• It degrades fibrin.

• It inhibits thrombin.

• It promotes platelet adhesion and aggregation.

• It activates plasminogen.