Hemoglobin Function Haldane Effect

The video tutorial explains the Haldane and Bohr effects, focusing on their differences and similarities. The Bohr effect describes how pH affects oxygen binding to hemoglobin, with low pH leading to oxygen release. The Haldane effect, on the other hand, involves the role of CO2 in oxygen release and vice versa. The tutorial delves into the molecular mechanisms, highlighting the role of lysine and arginine residues in CO2 binding. Practical implications, such as oxygen and CO2 exchange in the lungs and tissues, are also discussed.

What is the primary focus of the Bohr effect?

• How CO2 affects oxygen binding

• How pH affects oxygen binding

• How temperature affects oxygen binding

• How hemoglobin structure affects oxygen binding

According to the Bohr effect, what happens when there is a low pH?

• Oxygen binds more tightly to hemoglobin

• CO2 is released from hemoglobin

• Hydrogen ions are absorbed by hemoglobin

• Oxygen is released from hemoglobin

What does the Haldane effect primarily describe?

• The effect of pH on CO2 binding

• The effect of hemoglobin structure on CO2 binding

• The effect of CO2 on oxygen binding

• The effect of temperature on oxygen binding

In the Haldane effect, what happens when CO2 binds to hemoglobin?

• Hydrogen ions are released

• CO2 is converted to bicarbonate

• Oxygen binds more tightly

• Oxygen is released

Which amino acid is more likely to bind CO2 in the Haldane effect?

• Histidine

• Lysine

• Arginine

• Glutamine

Why is lysine more reactive in binding CO2 compared to arginine?

• Lysine is more abundant in hemoglobin

• Lysine has a localized lone pair

• Lysine has a delocalized lone pair

• Lysine is an enzyme

Where does the release of CO2 due to the Haldane effect primarily occur?

• In the kidneys

• In the liver

• In the lungs

• In the muscles

What happens to CO2 in metabolically active tissues according to the Haldane effect?

• It is stored in cells

• It is converted to oxygen

• It is exhaled

• It binds to hemoglobin

What principle governs the Haldane effect?

• Dalton's law

• Henry's law

• Boyle's law

• Le Chatelier's principle

What is the result of a high influx of oxygen in the lungs?

• Increased CO2 binding to hemoglobin

• Release of CO2 from hemoglobin

• Decreased oxygen binding to hemoglobin

• Increased oxygen binding to CO2