Catabolism of Glutaryl-S-CoA to Acetyl-S-CoA

The video tutorial explores the catabolic pathway of Glutaryl CoA, highlighting its pseudo-beta oxidation process. It explains the electron transfer mechanism leading to ubiquinol production in liver cells and discusses the formation of Crotonyl CoA. The tutorial also covers the ketogenic and glucogenic pathways in tryptophan catabolism, emphasizing the production of Acetyl CoA and its role in ketone body biosynthesis.

What is the primary difference between the catabolic pathway of Glutaryl-CoA and normal beta-oxidation?

• The first enzyme used in the pathway

• The type of coenzyme involved

• The location where the process occurs

• The presence of an additional enzyme

Which molecule acts as the initial electron acceptor from FADH2 in the electron transfer process?

• Cytochrome C

• Electron transferring flavoprotein

• Coenzyme Q

• NADH

What is the result of the spontaneous decomposition of Glutaconyl-CoA?

• Synthesis of ATP

• Production of NADH

• Release of carbon dioxide

• Formation of Acetyl-CoA

Which enzyme is responsible for the hydration of Crotonyl-CoA in the beta-oxidation pathway?

• NADH oxidoreductase

• Thiolase

• Enoyl-CoA hydratase

• Glutaryl-CoA dehydrogenase

What is the fate of Acetyl-CoA produced in amino acid oxidation during the fasted state?

• It is converted to glucose

• It enters the citric acid cycle

• It is used in ketone body biosynthesis

• It is stored as glycogen

How is tryptophan catabolism both glucogenic and ketogenic?

• It does not produce any energy molecules

• It only produces glucose

• It produces both glucose and ketone bodies

• It only produces ketone bodies

Which tissues can utilize ketone bodies produced by the liver?

• Heart and spleen

• Kidneys and lungs

• Muscle and brain

• Only the liver