Interview with Sir Patrick Vallance on COVID-19 vaccines

The video discusses the Pfizer vaccine's effectiveness based on clinical studies and real-world data. Initially, the vaccine shows 50% protection, increasing to 89% after 10 days. Real-world effectiveness may differ from clinical trials. Data from Israel and schools will provide further insights. It's crucial to understand that protection doesn't start immediately, and infections can occur within the first 10 days post-vaccination. Continuous data collection is essential to gauge real-world effectiveness.

What is the expected protection rate of the Pfizer vaccine from the day of vaccination to day 28?

• 70%

• 89%

• 100%

• 50%

Why is there no expected protection in the first 10 days after vaccination?

• The vaccine is not effective

• The vaccine is only a placebo

• The vaccine is administered incorrectly

• The immune system needs time to build up

What protection rate is observed from day 10 to day 21 according to the Joint Committee on Vaccination and Immunisation?

• 70%

• 100%

• 50%

• 89%

How do real-world outcomes of vaccine efficacy typically compare to clinical trial results?

• They are usually better

• They are usually worse

• They are unpredictable

• They are exactly the same

Why is it important to collect data from real-world scenarios like schools and other countries?

• To decide on the vaccine's distribution

• To determine the cost of the vaccine

• To understand the vaccine's effectiveness beyond clinical trials

• To confirm the vaccine's side effects