The Chemistry of Arynes (Benzyne)

The video explores the chemistry of airines, focusing on their structure, reactivity, and methods of production. It highlights the work of chemists like Georg Vidig and John Roberts in understanding benzine intermediates. Various methods to produce airines are discussed, including reactions involving halobenzenes and anthranilic acid. The video also covers the reactivity of airines, their tendency to undergo cycloaddition, and their applications in synthetic chemistry.

Which chemist is known for confirming the nature of the benzine intermediate using isotopic labeling?

• John Roberts

• Linus Pauling

• Georg Vidig

• Marie Curie

What is a common feature in the methods of producing benzine?

• Formation of a carbon ion adjacent to a leaving group

• Formation of a stable intermediate

• Use of a strong acid

• Direct substitution reactions

Why are benzines typically not isolated?

• They are too reactive

• They are too stable

• They are not useful in reactions

• They require high temperatures

What happens when benzine reacts with an electron-withdrawing substituent adjacent to the triple bond?

• The para product is favored

• No reaction occurs

• The meta product is favored

• The ortho product is favored

What is a potential reaction of benzine in the absence of nucleophiles?

• Oxidation

• Reduction

• Dimerization

• Hydrogenation

In a Diels-Alder reaction, what role does benzine play?

• Diene

• Catalyst

• Dienophile

• Inhibitor

What is the significance of benzine's structure in synthetic applications?

• It is easily isolated

• It is non-reactive

• It has a strained structure

• It is highly stable