Macroautophagy | Transcriptional Regulation: Lesson 2

Macroautophagy | Transcriptional Regulation: Lesson 2

Assessment

Interactive Video

Health Sciences, Biology

University - Vocational training

Hard

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The video discusses transcriptional regulation of macroautophagy, focusing on transcriptional repressors like Zach Scan 3, HSF1, TCF4, XBP1, FXR, and NF Kappa B. Each repressor's role in either suppressing or enhancing macroautophagy is explained, highlighting their interactions with various proteins and pathways. The video emphasizes the dual functions of some repressors, such as XBP1 and NF Kappa B, in both upregulating and downregulating specific proteins, impacting the macroautophagy pathway.

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7 questions

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1.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which transcriptional repressor is known to enter the nucleus during the fed state to suppress macroautophagy?

XBP1

TCF4

Zaktan 3

HSF1

2.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the primary effect of HSF1 on P62 expression?

It stabilizes P62

It has no effect on P62

It downregulates P62

It upregulates P62

3.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

How does TCF4 regulate P62 expression?

By upregulating P62

By downregulating P62

By stabilizing P62

By degrading P62

4.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What dual role does XBP1 play in the macroautophagy pathway?

It has no effect on proteins

It both upregulates and downregulates proteins

It only downregulates proteins

It only upregulates proteins

5.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which transcriptional repressor is considered the opposite of PPAR Alpha?

FXR

Zaktan 3

HSF1

NF Kappa B

6.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What effect does NF Kappa B have on beclin 1?

It stabilizes beclin 1

It downregulates beclin 1

It degrades beclin 1

It upregulates beclin 1

7.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which transcriptional repressor can inhibit E2F1, affecting macroautophagy?

FXR

NF Kappa B

XBP1

HSF1