Exercise Physiology | mTORC1 and Muscle Protein Synthesis

The video explains the role of mTORC1 in muscle protein synthesis and hypertrophy. It details how amino acids, particularly leucine and arginine, activate mTORC1, which is crucial for muscle growth. The video also covers the mechanisms of mTORC1 activation, including the involvement of Gator proteins and Rag GTPases. Additionally, it discusses the functions of mTORC1 in stimulating protein synthesis and inhibiting autophagy, highlighting the importance of amino acids and other factors like glucose and growth factors in this process.

What is the role of the protein complex mTORC1 in muscle protein synthesis?

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What is the significance of myofibril agenesis in muscle hypertrophy?

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Explain the importance of amino acids in the activation of mTORC1.

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Describe the process of translocation of mTORC1 from the Golgi apparatus to the lysosome.

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How do BCAAs, particularly leucine, influence the activation of mTORC1?

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Discuss the role of arginine in the activation of mTORC1.

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What are the three key factors required for the activation of mTORC1?

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Explain how mTORC1 inhibits autophagy and protein degradation.

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What is the relationship between insulin signaling and mTORC1 activation?

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What is the function of HMB in relation to muscle protein synthesis?

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