Lactate Dehydrogenase

The video explains the role of lactate dehydrogenase in regenerating NAD during anaerobic conditions. It discusses NADH production in glycolysis and the TCA cycle, and how enzymes like cytochrome C oxidase and NADH ubiquinone oxidoreductase are affected by the absence of oxygen. The video highlights the importance of lactate dehydrogenase in maintaining glycolysis by converting pyruvate to lactate, especially in anaerobic conditions like during intense exercise or heart attacks. It also compares ATP production in aerobic and anaerobic metabolism, emphasizing the inefficiency of anaerobic glycolysis.

Explain the role of NADH in glycolysis and the TCA cycle.

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Describe the consequences of a lack of oxygen on the function of cytochrome C oxidase.

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What happens to NADH levels when cytochrome C oxidase is not functioning?

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What are the potential outcomes if NAD+ levels decrease in a cell?

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What is the primary function of lactate dehydrogenase in cellular metabolism?

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How does lactate dehydrogenase help in regenerating NAD?

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What is the significance of the reaction catalyzed by lactate dehydrogenase?

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Explain how the buildup of lactate can affect energy production in cells.

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What is the relationship between lactate production and anaerobic metabolism?

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Discuss the impact of prolonged anaerobic metabolism on heart cells.

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