LDL-mediated Cholesterol Delivery to Cells

The video explains how LDL delivers cholesterol to cells, highlighting its role in stabilizing cell membranes and its transformation into molecules like steroids and bile acids. Cholesterol is packaged as cholesteryl ester within lipoproteins. Cells regulate cholesterol intake through LDL receptors, which increase when cholesterol is low. LDL particles bind to these receptors and are internalized via receptor-mediated endocytosis. The endosome fuses with a lysosome, breaking down LDL components. Cholesterol is then processed and transported to cell membranes or converted into other molecules.

How does cholesterol affect the fluidity of cell membranes?

What is the primary role of LDL in the body?

Describe the process by which a cell increases its cholesterol uptake when levels are low.

What happens to LDL receptors after they have internalized LDL particles?

Explain the role of lysosomes in the degradation of LDL particles.

What is cholesteryl oleate and how is it related to cholesterol metabolism?

How does the endoplasmic reticulum contribute to cholesterol processing in cells?