Factor V Leiden | Causes, Pathophysiology, Symptoms, Diagnosis, Treatment

The video tutorial discusses Factor 5 Leiden, an autosomal dominant hematologic condition that increases the risk of thrombosis. It covers the genetic basis, prevalence, and pathophysiology of the condition, highlighting the role of the R506Q mutation and incomplete penetrance. Clinical features such as venous thromboembolism and associated risks are explored. The tutorial also outlines diagnostic methods, including genetic testing, and treatment options like anticoagulation therapy. The video concludes with a call to explore further hematology topics.

What is the significance of the R506Q mutation in Factor 5 Leiden?

Identify the common clinical features associated with venous thromboembolism in Factor 5 Leiden.

What are the potential risks of Factor 5 Leiden during pregnancy?

Discuss the genetic implications of Factor 5 Leiden for family members.