The Nuclear Pore Complex: Nuclear Import, Export, & RAN

The video tutorial explains the nuclear pore complex (NPC) and its crucial role in regulating the import and export of molecules in and out of the nucleus. It details the nuclear import process, highlighting the importance of nuclear localization sequences (NLS) and the role of importin and RAN GTPase. The tutorial also covers the nuclear export process, focusing on nuclear export sequences (NES) and the function of exportin and RAN GTPase. The mechanisms ensure that only specific proteins with the correct sequences are transported, maintaining cellular function.

What is the function of the nuclear export sequence (NES) in protein transport?

Discuss the differences between the nuclear localization sequence (NLS) and the nuclear export sequence (NES).

What happens to RAN after it facilitates the export of proteins from the nucleus?