Von Willebrand Disease | Pathophysiology, Types, Symptoms and Treatment

The video provides a comprehensive overview of Von Willebrand disease, the most common inherited bleeding disorder. It explains the role of Von Willebrand factor (VWF) in hemostasis, platelet aggregation, and adhesion. The video discusses the clinical features, types, and genetic inheritance patterns of the disease. It also covers diagnostic methods, the impact of blood type, and treatment options, including desmopressin and factor VIII transfusions. Additionally, the video addresses acquired Von Willebrand disease and its association with conditions like aortic stenosis and Wilms tumor.

What is Von Willebrand disease and why is it significant?

Describe the inheritance patterns associated with Von Willebrand disease.

What role does von Willebrand factor play in hemostasis?

List some clinical features of Von Willebrand disease.

How is Von Willebrand disease classified?

What are the differences between Type 1 and Type 2 Von Willebrand disease?

How can acquired Von Willebrand disease occur?

Explain the significance of blood type in the context of Von Willebrand disease.

What are the treatment options for Von Willebrand disease?

What is the role of desmopressin in the management of Von Willebrand disease?