Remdesivir & SARS-CoV-2 (COVID-19) | Mechanism of Action, Adverse Effects, Anti-Viral Properties

The video tutorial discusses Remdesivir, an antiviral initially developed for Ebola, now explored for COVID-19 treatment. It explains Remdesivir's mechanism as a nucleotide analog inhibiting RNA synthesis, its adverse effects like nausea and liver enzyme elevation, and its potential against coronaviruses. The tutorial covers in vitro and in vivo studies, highlighting ongoing research and the possibility of viral resistance due to mutations.

What evidence supports the use of Remdesivir against COVID-19?

Describe the role of the EXO ribonuclease in the viral RNA synthesis process.

What are the implications of mutations in the EXO ribonuclease for Remdesivir efficacy?

Summarize the current knowledge about Remdesivir as a therapeutic option for coronaviruses.