Mechanisms of Spasticity and Baclofen [Macroscopic view ONLY]

The video explains the connection between upper and lower motor neurons, focusing on spasticity. It describes how spasticity results from an imbalance of excitatory and inhibitory signals, particularly in the absence of descending inhibitory input. The stretch reflex and its exaggeration in spasticity are discussed, along with the effects of upper motor neuron lesions. The video also covers the role of Baclofen in managing spasticity by inhibiting specific neurons, and concludes with a discussion on flexor synergy in upper motor neuron lesions.

Discuss the differences between flexor and extensor spasticity in upper motor neuron lesions.

How do descending inhibitory tracts affect lower motor neurons?

What mechanisms lead to the exaggerated stretch reflex observed in spasticity?

Explain the role of the premotor cortex in regulating the stretch reflex.