How Herpes Can Actually Be Good For You

Herpesviruses, known for causing lifelong infections like mono and chickenpox, may also benefit the immune system by training innate immunity. This concept, called trained immunity, suggests that herpesviruses keep the immune system on high alert, potentially protecting against other pathogens. Research in mice shows that latent herpes infections can confer resistance to deadly bacteria. While human studies are less definitive, there are indications of similar benefits. However, trained immunity might also lead to autoimmunity. Further research could help harness these benefits without infection, possibly through vaccines.

What is the significance of the term 'trained immunity' and when was it proposed?

What are the potential downsides of trained immunity?

How might studying herpesviruses lead to advancements in vaccines?