Bronchodilators Part 1: Principles of Respiratory Airflow and Development of Selective Drugs

The video tutorial covers pulmonary drugs, focusing on bronchodilators used to treat asthma and COPD. It explains airway resistance using Poiseuille's law and the role of bronchodilators in reducing resistance. The tutorial delves into the mechanisms of bronchodilation, highlighting beta-2 adrenoceptor agonists and their selectivity. It also discusses the importance of Structural Activity Relationship studies in drug discovery, using salbutamol as an example to illustrate enantiomeric differences and their impact on drug efficacy.

How do structural differences in drugs affect their pharmacology and receptor selectivity?

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Discuss the challenges associated with developing pure enantiomers of bronchodilators.

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What are the expected outcomes of the next tutorial regarding bronchodilation?

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