Alcohol Dehydrogenase: Physiology, Biochemistry, and Mechanism

The video explores ethanol metabolism, highlighting its conversion to acetyl CoA via alcohol dehydrogenase. Ethanol is treated as a toxic compound, and its metabolism involves conversion to acetaldehyde, primarily in the liver. The video discusses the role of alcohol dehydrogenase, its mechanism, and the medical implications of enzyme mutations, particularly in certain ethnic groups. It also covers the metabolism of other alcohols like methanol and isopropyl alcohol, and alternative pathways for ethanol metabolism.

What are the implications of alcohol dehydrogenase deficiencies in certain ethnic groups?

Explain the process of how acetaldehyde is formed from ethanol.

What are the different types of alcohols that can be metabolized by alcohol dehydrogenase?

Discuss the significance of the microsomal system in ethanol metabolism.