Phenylalanine, Tyrosine Catabolism to Acetoacetate

This video explains the catabolic pathways of phenylalanine and tyrosine, highlighting their convergence and the role of enzymes like phenylalanine hydroxylase. It discusses the fasting state, energy production, and the conversion of amino acids into ketogenic and glucogenic products. The video also covers disorders such as phenylketonuria and alkaptonuria, caused by enzyme deficiencies, and the impact of genetic mutations on these pathways.

What are the consequences of a deficiency in phenylalanine hydroxylase?

Discuss the relationship between phenylketonuria and dietary restrictions.

What is the role of aspartame in relation to phenylalanine and its implications for individuals with phenylketonuria?

Identify and explain one other disorder associated with the catabolic pathways of phenylalanine and tyrosine.