Wolff-Kishner Reduction

The video tutorial explains the Wolff-Kishner reduction, a method to reduce aldehydes and ketones to alkanes under basic conditions. It covers the reaction mechanism, involving hydrazine and a strong base, and highlights its applications in pharmaceutical synthesis. The tutorial also discusses modifications for milder conditions and complex strategies in organic synthesis, such as pyrrole alkylation. The Wolff-Kishner reduction remains a vital tool for organic chemists.

Explain the significance of the carbanion formed during the Wolff-Kishner Reduction.

What modifications have been made to the original Wolff-Kishner protocol?

How does the Wolff-Kishner Reduction highlight the utility of carbonyl compounds in organic synthesis?