What Causes Treatment Resistant Depression?

Dr. Tracy Marks discusses treatment resistance in depression, highlighting the STAR D trial's findings on antidepressant effectiveness. She explains treatment resistance, medication intolerance, and factors affecting antidepressant response. Physical conditions like hormone imbalances and chronic pain can complicate treatment. Some medications may cause depression as a side effect, and alternative options should be considered.

What role do side effects play in determining treatment resistance?

What is the therapeutic range and why is it important?

What are some medications that can cause depression as a side effect?