Fructose Metabolism: Absorption, Fructolysis, Regulation and Role in Obesity

The video tutorial explores fructose, a monosaccharide found in fruits and high fructose corn syrup. It details how fructose is absorbed in the intestine via glute 5 and glute 2 transporters and metabolized in the liver. The tutorial compares fructose metabolism with glycolysis, highlighting the lack of regulation in fructose metabolism, which can lead to excessive triglyceride production. This unregulated process is linked to health issues like obesity, diabetes, and non-alcoholic fatty liver disease.

Discuss the regulation of fructose metabolism compared to glucose metabolism.

What happens to pyruvate after fructose is metabolized?

What enzymes are involved in the conversion of fructose to fatty acids?

How does the lack of regulation in fructose metabolism contribute to obesity and diabetes?