When is foreign business prohibited under US law?

The video tutorial explains U.S. trade restrictions, focusing on embargoes and targeted sanctions set by the Department of Treasury's Office of Foreign Asset Control. Embargoes completely prohibit trade with certain countries like Iran, Sudan, and Cuba, while targeted sanctions allow limited trade with nations such as North Korea and Syria. Specially designated entities require permits for business dealings due to their potential role in circumventing sanctions. The regulatory framework aims to control trade based on human rights and other standards.

What must a U.S. company do to conduct business with specially designated entities?

What are some reasons that might lead to the imposition of restrictions on foreign countries?