Apoptosis | The Mitochondrial Pathway

The video tutorial by Kevin Tolkoff explores apoptosis, a form of programmed cell death, focusing on the mitochondrial pathway. It explains the role of zymogen cascades, particularly the activation of pro-death proteins like cytochrome C, AIF, and Diablo, and the inhibition of pro-survival proteins such as BCL-2. The tutorial also covers the function of caspases in executing apoptosis and the impact of external stimuli like UV radiation on triggering cell death. The video sets the stage for further exploration of the extrinsic pathway in subsequent tutorials.

How do pro-survival proteins like BCL-2 prevent apoptosis?

What is the significance of executioner caspases in the apoptosis process?

What is the function of apoptosis-inducing factor (AIF) in the apoptosis process?

Describe the role of Diablo in the regulation of apoptosis.