Practice Problem: Reaction of a Terminal Alkyne

The video tutorial explains a practice problem involving an alkyne subjected to three reaction conditions. It begins with an overview of the problem and the role of the Grignard reagent, which is used in an unorthodox manner to form an acetylide anion. The acetylide anion then attacks an epoxide, leading to ring opening. Finally, an aqueous acidic workup results in the formation of an alcohol product. The tutorial emphasizes critical thinking in understanding the reactions and the importance of recognizing alternative pathways in organic chemistry.

What happens to the epoxide during the reaction, and what is the outcome?

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Summarize the overall product of the sequence of reactions discussed.

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